To reveal a potential combined effect of pollution and continuos warming towards freshwater organisms, the molecular responses of stress and toxicity were compared du-ring two years in the bivalve mollusks Anodonta anatina from the cooling pond of Khmelnytskyi Nuclear Power Plant (N-group) and from the ponds in the forestry (F-group) and agricultural (A-group) areas. Using Classification and Regression Tree (CART) software on the basis of a set of studied markers, characteristics for the distinguishing of N-group were selected. Firstly, it was the constantly elevated level of the vitellogenin-like protein in gonads and hemolymph of male specimens that witness the effect of endocrine disruption. The mussels of N-group demonstrated on oxidative injury with highest values of the Index of inter-seasonal variability for oxidized glutathione and metallothionein-related thiols among three groups, and constantly high level of apoptotic activity in the digestive gland. Remarkably higher levels of copper and cadmium within the tissues were detected in the N-group reflecting the industrial pollution. These metals were preferentially bound to metal-buffering protein metallothionein. A combination of these characteristics demonstrates that stable elevated temperature jointly with industrial pollution caused a partial apoptotic elimination of cells with the nuclear lesions and provoked the exceeding of resistance of stress-related responses and reproduction-related functions in the mussels.

• Бойко Микола Іванович (технічні науки)

  Якщо, ви не знайшли інформацію про автора(ів) публікації, маєте бажання виправити або відобразити більш докладну інформацію про науковців України запрошуємо заповнити "Анкету науковця"