The estimation of parameters of chromosomal instability in human lymphocytes and buccal cells of the winterers of VI UAE was carried out. We did not reveal differences between the average rates of chromosomal aberrations and the levels of micronucleated cells before and at the end of the expedition, but the levels of premature centromeric division and C-anaphases changed significantly. The investigation of the dynamics of micronucleus frequencies revealed a decreasing of the micronuclei rate during the expedition and its restoring to the initial level after returning to Ukraine.

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