Glioblastoma is the most aggressive type of brain tumor classified as type 4 astrocytoma according to 5th edition of the World Health Organization сlassification of tumors of the central nervous system. It is a cancer that begins in the glial cells, which are the supporting cells of the brain. Glioblastoma is a rare type of brain tumor and accounts for about 15 % of all brain tumors. It is most commonly found in adults over the age of 50, and men are more likely to develop it than women. The symptoms of glioblastoma can vary depending on the location of the tumor in the brain. Common symptoms include headaches, nausea, vomiting, and changes in vision. Other symptoms can include seizures, changes in behavior or personality, and difficulty with speech or movement. The standard treatment for glioblastoma is a combination of surgery, radiation therapy, and chemotherapy. Surgery is usually the first step in treatment, with the goal of removing as much of the tumor as possible. Radiation therapy and chemotherapy are typically used to kill any remaining cancer cells. However, despite these treatments, the prognosis for glioblastoma is generally poor, with most patients surviving for less than two years after diagnosis. Overall, glioblastoma is a highly aggressive brain tumor with poor prognosis. The standard treatment is a combination of surgery, radiation therapy and chemotherapy. Recent research has focused on developing new treatments, such as targeted therapies and immunotherapies, which have shown promising results in clinical trials.

• Смоланка Володимир Іванович (1961–) (медичні науки)

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